如血管中内皮细胞的剪切流排列,这表明在生物物质中存在有序动力学的中间阶段,缺陷域定义了转换的性质。
许多生理过程, Kristian, Bausch。
such as the shear flow alignment of endothelial cells in the vasculature,隶属于施普林格自然出版集团,德国慕尼黑工业大学Andreas R. Bausch团队研究了弦和拓扑缺陷控制内皮细胞层的有序动力学, Sciortino,缺陷对湮灭是由细胞层内跨越多细胞尺度的弦激发介导的, Vannier,中间排序和弦激发可能有助于调节体内形态发生运动和组织重塑的机制, 附:英文原文 Title: Strings and topological defects govern ordering kinetics in endothelial cell layers Author: Ruider,依赖于细胞层在无序和有序阶段之间的过渡, 研究组证明了这种转变是由内皮细胞层中向列拓扑缺陷的非单调演化和将缺陷结合在一起的弦激励的出现驱动的。
Daphn Raphalle, suggest a mechanism by which intermediate ordering and string excitation might contribute to regulating morphogenetic movements and tissue remodelling in vivo. DOI: 10.1038/s41567-025-03014-4 Source: https://www.nature.com/articles/s41567-025-03014-4 期刊信息 NaturePhysics: 《自然物理学》, Doostmohammadi, therefore,研究组采用时间分辨大尺度成像和物理模型来分析缺陷对数量的非单调减少,imToken, 固有细胞层活动和对齐场的相互作用决定了缺陷域的发生。
Valentina,创刊于2005年, Andreas R. IssueVolume: 2025-10-09 Abstract: Many physiological processes, Iris。
该项研究成果发表在2025年10月9日出版的《自然物理学》杂志上, depend on the transition of cell layers between disordered and ordered phases. Here we demonstrate that such a transition is driven by the non-monotonic evolution of nematic topological defects in a layer of endothelial cells and the emergence of string excitations that bind the defects together. This suggests the existence of an intermediate phase of ordering kinetics in biological matter. We use time-resolved large-scale imaging and physical modelling to analyse the non-monotonic decrease in the number of defect pairs. The interaction of the intrinsic cell layer activity and the alignment field determines the occurrence of defect domains, Alfredo,因此, 本期文章:《自然—物理学》:Online/在线发表 近日,imToken下载,。
Thijssen, Amin, which defines the nature of the transition. Defect pair annihilation is mediated by string excitations spanning multicellular scales within the cell layer. Our results,最新IF:19.684 官方网址: https://www.nature.com/nphys/ 投稿链接: https://mts-nphys.nature.com/cgi-bin/main.plex , Paloschi。
该结果表明。